RT Journal Article SR Electronic T1 Physical Therapist Management of Stiff Person Syndrome in a 24-Year-Old Woman JF Physical Therapy JO Phys Ther FD American Physical Therapy Association SP 1403 OP 1411 DO 10.2522/ptj.20100303 VO 91 IS 9 A1 Hegyi, Christopher A. YR 2011 UL http://jcore-reference.highwire.org/content/91/9/1403.abstract AB Background and Purpose Stiff person syndrome is a rare neurological disorder characterized by stiffness and painful spasms primarily in the trunk and lower extremities. The role of physical therapy in the management of this disorder is disputed and the efficacy of specific interventions is unknown. Case Description The patient was a 24-year-old woman with a 1-year history of stiff person syndrome who received outpatient physical therapy over the course of 15 weeks. She had pain, muscle spasms, gait anomalies, and range-of-motion deficits, which affected her left lower extremity. Physical therapy interventions consisted of ultrasound, soft tissue mobilizations, manual stretching, and exercise. She also was fitted for a custom-made ankle-foot orthosis. Outcome This patient showed decreased pain and muscle spasms, as well as improvements in gait and range of motion. Discussion Stiffness and spasms interfere with the ability of these patients to fully mobilize affected joints, and they are at risk of developing further complications. Physical therapy may have a role in the management of this disease, as these patients need to be taught how to properly stretch and maintain joint mobility as a lifelong commitment.