Safety of Aerobic Exercise in People With Diabetic Peripheral Neuropathy: Single-Group Clinical Trial

Figures

Figure 1.

Consolidated Standards of Reporting Trials (CONSORT) diagram.

Figure 2.

Frequency histogram of exercise-related adverse events that required intervention during each week of the 16-week exercise program.

Figure 3.

Frequency histogram of the percentages of participants reporting various types of adverse events.

Table 1.

Progression of Intensity and Target Heart Rate (HR) Duration During Aerobic Exercise Intervention^{^a}

↵^a V̇o₂R=oxygen uptake reserve, individually calculated for participants on the basis of the results of the graded maximal exercise test. Average heart rate target values were 102.4 (SD=11.7) beats per minute (bpm) for 50% V̇o₂R, 109.5 (SD=13.3) bpm for 60% V̇o₂R, and 115.8 (SD=14.7) bpm for 70% V̇o₂R.

Table 2.

Participant Characteristics (N=18)^{^a}

↵^a Values are reported as numbers of participants, unless otherwise indicated. bpm=beats per minute.
^b For autonomic symptoms, “yes” was recorded if the participant reported the presence of an autonomic symptom (eg, fainting, impotence, constipation, or loss of bladder or bowel control).

Table 3.

Outcome Measures Before and After the Exercise Intervention^{^a}

↵^a V̇o₂peak=peak oxygen uptake during a graded exercise test, MFI-20=Multidimensional Fatigue Inventory, HbA_1c=glycated hemoglobin A_1c, HOMA-IR=homeostasis model assessment–insulin resistance index, HDL=high-density lipoprotein, LDL=low-density lipoprotein, BMI=body mass index, PSQI=Pittsburgh Sleep Quality Index.
^b P≤.05, as determined with a 2-tailed paired t test.

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eFigure (PDF) (35 KB) - This data supplement contains an eFigure:
- eFigure. Scatterplot of the change in general fatigue and the percentage of exercise sessions attended.