Pelvic-Floor Muscle Rehabilitation in Erectile Dysfunction and Premature Ejaculation

Pierre Lavoisier; Pascal Roy; Emmanuelle Dantony; Antoine Watrelot; Jean Ruggeri; Sébastien Dumoulin

doi:10.2522/ptj.20130354

Figures

Figure 1.

Flow diagram of study participants and number of analyzed sessions. ED=erectile deficiency, PE=premature ejaculation.

Figure 2.

Sample from the recordings made during a biofeedback session. The intracavernous pressure changes (the peaks) were provoked by voluntary contractions of the ischiocavernosus muscle starting from a baseline at about 100 mm Hg (135.95 cm H₂O).

Figure 3.

Example of the adjustable mask. Each peak represents the change in intracavernous pressure during a single ischiocavernosus muscle contraction. The rectangle that surrounds each peak is the form to reproduce during each contraction, starting from the baseline. This algorithm-created mask is adjustable in each of its components: duration (width), amplitude (height), and ischiocavernosus muscle fatigue index (angle α).

Tables

Table 1.

Drug Treatments Given to the Participants^{^a}

↵^a ED=erectile deficiency, PE=premature ejaculation, PDE5-I=phosphodiesterase type 5 inhibitor, SSRI=selective serotonin reuptake inhibitor.
^b Tricyclic antidepressant.

Table 2.

Parameters Stemming From the Linear Mixed-Effects Model Applied to Participants in the ED and PE Groups Over the First 20 Sessions^{^a}

↵^a ED=erectile deficiency; PE=premature ejaculation; SE=standard error; max ΔP=maximum ΔP (the average contraction-generated difference in intracavernous pressure, measured during the highest moving average of the best 2 minutes of each session); max baseline=maximum baseline (the intracavernous pressure plateau at full erection, measured during the highest moving average of the best 2 minutes of each session).
^b P values resulting from ED group vs PE group comparisons using Wald tests on the parameters estimated from the linear mixed-effects models (detailed in the “Method” section of the text).
^c Estimated mean linear trend.
^d P value <.05 resulting from a Wald test assessing whether the coefficient is different from zero.
^e Estimated mean starting value.

Table 3.

Main Indicators of ICP per Session^{^a}

↵^a Observed means over the first 5 sessions and model-estimated slope obtained with up to 20 sessions. ICP=intracavernous pressure, ED=erectile deficiency; PE=premature ejaculation; SE=standard error; max ΔP=maximum ΔP (the average contraction-generated difference in intracavernous pressure, measured during the highest moving average of the best 2 minutes of each session); max baseline=maximum baseline (the intracavernous pressure plateau at full erection, measured during the highest moving average of the best 2 minutes of each session).
^b Participants who had at least 5 therapy sessions.
^c (Mean at fifth session − mean at first session)/4.
^d The effect of one session obtained with the linear mixed-effects model considering up to 20 sessions.