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On “Effectiveness of trigger point dry needling…” Cotchett MP, Munteanu SE, Landorf KB. Phys Ther. 2014;94:1083–1094.

James Dunning, Raymond Butts, Thomas Perreault
DOI: 10.2522/ptj.2014.94.11.1677 Published 1 November 2014
James Dunning
J. Dunning, DPT, MSc, MMACP (UK), MAACP (UK), FAAOMPT, Director, AAMT Fellowship in Orthopaedic Manual Physical Therapy President, Alabama Physical Therapy & Acupuncture, Montgomery, AL 36117 (USA).
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Raymond Butts
R. Butts, PhD, DPT, MSc (NeuroSci), Cert SMT, Cert DN, Senior Faculty, AAMT Fellowship in Orthopaedic Manual Physical Therapy, Senior Physical Therapist, Research Physical Therapy Specialists, Columbia, South Carolina.
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Thomas Perreault
T. Perreault, DPT, OCS, Cert SMT, Cert DN, Senior Faculty, AAMT Fellowship in Orthopaedic Manual Physical Therapy, Senior Physical Therapist, Portsmouth Physical Therapy, Portsmouth, New Hampshire.
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It was with interest and some concern that we read the report by Cotchett et al1 published in the August 2014 issue of PTJ. Although the authors reported statistically significant differences in first-step pain and foot pain in favor of trigger point dry needling over sham dry needling, it appears that the actual palpatory methods used by Cotchett et al1 to identify the location of the target trigger points and, therefore, the entry point, angulation, and depth of needle insertion have not yet been found to possess accurate diagnostic validity or acceptable intra- or inter-examiner reliability for muscles in the foot or lower leg. Therefore, the results of the study by Cotchett et al,1 including the reported frequency counts of myofascial trigger points in specific foot intrinsic and lower leg muscles, should be questioned, or at least viewed cautiously. There are several original trials, literature reviews, and meta-analyses that support our contention on this issue.

In a recent systematic review, Tough et al concluded, “There is a lack of robust empirical evidence validating the clinical diagnostic criteria [for trigger point identification or diagnosis] proposed by both Travell & Simons (1999) and Fischer (1997).”2 In another systematic review on the reliability of physical examination for the diagnosis of myofascial trigger points, Lucas et al concluded, “There is no accepted reference standard for the diagnosis of trigger points, and data on the reliability of physical examination for trigger points is conflicting.”3 In addition, a predictable pattern of pain referral and the local twitch response are each no longer considered sufficient or necessary for diagnosing trigger points.2–4 Yet, regardless of the existing evidence, Cotchett et al1 still decided to use “a characteristic pattern of referred pain” and “a local twitch response” as 2 of the 4 criteria for the identification and diagnosis of myofascial trigger points in the foot and lower leg.

We would like to encourage Cotchett et al1 to provide evidence from an original, peer-reviewed experimental study, not a textbook written by Travell and Simons,5,6 that supports the diagnostic accuracy and reliability for the use of a “characteristic pattern of referred pain” or the presence of “a local twitch response” in making the diagnosis of a myofascial trigger point within the quadratus plantae, flexor digitorum brevis, or other intrinsic muscles of the foot. To our knowledge, such a study does not exist, and, according to Myburgh et al,4 the gluteus medius (kappa range=.29 to .49) and the quadratus lumborum (kappa range=.36 to .50) are the only muscles in the human body with distinct and predictable pain referral patterns that have acceptable reproducibility on manual examination. Furthermore, in a systematic review on the reliability of physical examination for the diagnosis of myofascial trigger points, Lucas et al3 found an unacceptable interrater reliability range (kappa range=−.05 to .57) for the local twitch response. Therefore, the internal validity of the Cotchett et al1 study appears to be jeopardized.

After reviewing 9 studies on reliability, Lucas et al concluded, “At present, there is no data on the reliability of pinpointing the exact location of active trigger points…. The existing data on reliability pertain only to agreeing if a muscle has the signs of a trigger point and not the exact location of the taut band or the nodule within the taut band.”3 Lew et al7 reported inter-examiner agreement of only 21%, and Sciotti et al8 reported error rates of 3.3 to 6.6 cm among examiners attempting to identify the specific location of trigger points in the upper trapezius muscle. In another recent literature review, Myburgh et al4 found poor inter-examiner reliability of manual palpation of trigger points in various muscle groups. Only “tenderness” of the upper trapezius muscle, not the actual location of the trigger point, was found to be moderately reliable. More recently, Myburgh et al9 similarly reported “good agreement between experienced practitioners” for the “presence or absence” of a clinically relevant trigger point in the upper trapezius muscle; however, like the many other studies,10–14 Myburgh et al9 failed to investigate the inter-rater reliability for determining the specific location of the trigger point within the target muscle.

According to Lucas et al, “It is not yet evident that examiners can agree on the precise location of an active TrP [trigger point]; hence, they cannot be relied upon to accurately insert the needle into the nodule of the taut band.”3 If clinicians are not able to reliably identify the exact location of trigger points,3,4,9 we are interested to know how Cotchett et al1 were able to accurately locate and verify needle placement in myofascial trigger points in muscles such as the quadratus plantae or the flexor digitorum brevis. Given that high-quality evidence suggests that manual examination for identifying the specific location of the myofascial trigger point is not a valid2,4,9 or reliable3,4,7,8 process, we encourage the authors to disclose how they determined the frequency counts for the presence of myofascial trigger points within specific muscles of the foot and lower leg (eg, 132 myofascial trigger points for the quadratus plantae muscle and 92 myofascial trigger points for the flexor digitorum brevis muscle in the real dry needling group). Furthermore, in the absence of guided imagery technology, we are curious how Cotchett et al1 were able to differentiate needle placement for the quadratus plantae muscle (within the second layer of the plantar foot) and the flexor digitorum brevis muscle (within the first layer of the plantar foot).

Although the authors cited a previous “consensus” study15 that Cotchett and colleagues authored in an attempt to justify leaving the needles in situ for a 5-minute duration after repeated pistoning (“withdrawn partially and advanced repeatedly”), it should be noted that 93% (28 of 30) of the participants on the Delphi panel practiced dry needling according to the Travell and Simons5,6 myofascial trigger point model, with just 7% (2 of 30) of panel participants having previous training or practice patterns in Western medical or traditional Chinese acupuncture.15 Furthermore, none of the 3 observational studies16–18 cited by Cotchett and colleagues15,19 actually left needles in situ for just 5-minute durations. Aside from one cohort study that treated plantar heel pain with a single lidocaine injection in which the needle was immediately removed upon dispensing the injectate,16 one case series used manual acupuncture and left the needles in place for 15 minutes,18 and the other case series used electroacu-puncture and left the needles in place for 20 minutes.17 Additionally, a recent randomized controlled trial of patients with chronic plantar fasciitis reported a 69% reduction in foot pain and an 80% success rate following 5 weeks of electroacupuncture where the needles were left in place for a duration of 30 minutes.20

In short, no previous case series,17,18 cohort study,16 or randomized trial20 has left the needles in place for just 5 minutes when treating patients with chronic plantar fasciitis; thus, we were surprised that Cotchett et al1 chose to limit the dosage to just 5 minutes in their recent trial on the use of dry needling for plantar heel pain. The authors' justification should be based on more than a “consensus”15 opinion, comprising 28 of 30 panel members who were trained in dry needling according to the narrowly focused21 muscular “trigger point only” Travell and Simons5,6 model—that would seem a little biased.

Notably, there is robust evidence from a recent meta-analysis22 that placement of needles in distal points of the upper and lower extremities activates specific brain areas such as the primary and secondary somatosensory cortex, insula, anterior cingulate cortex, and thalamus that are responsible for the sensory discrimination aspects of pain, commonly referred to as “deqi” (ie, soreness, aching, dull pain). According to functional magnetic resonance imaging and positron emission tomography studies,23–29 dry needling also has been shown to activate areas of the brain and brain stem associated with descending pain inhibition such as the periaqueductal gray area, raphe nuclei, and locus coeruleus30,31 while deactivating the limbic and paralimbic areas that modulate the cognitive and affective dimensions of pain.22 In the main, needles inserted into the body for the “central effects” on pain have typically been left in situ for between 8 and 25 minutes.23–29 In this light, we find it odd that Cotchett et al1 chose to confine the duration of their dry needling treatment to just 5 minutes.

Although the etiology of plantar heel pain remains unknown, it seems to be well accepted in the existing literature that the proximal attachment of the plantar aponeurosis, the medial tubercle of the calcaneus, is most often reported by patients with plantar fasciitis as the origin of symptoms and the site of greatest discomfort.32–34 Moreover, although the plantar pain may initially present as diffuse, it usually localizes to the area of the medial calcaneal tuberosity with time.33 Considering that 3 of the 4 previous studies on dry needling in patients with chronic plantar heel pain specifically targeted the insertion of the plantar fascia at or near the medial tubercle of the calcaneus,16,17,20 we find it baffling why Cotchett et al1 chose to omit needling of this key anatomic feature, instead focusing solely on muscular “trigger points” using manual palpation techniques that have yet to be validated or found to be reliable in their ability to locate such. Had Cotchett et al1 targeted the insertion of the plantar fascia at or near the medial tubercle of the calcaneus16,17,20 and left the needles in place for 15 minutes,18 20 minutes,17,35 or 30 minutes20 as previous studies have done in patients with chronic plantar heel pain, perhaps the between-group difference in first-step pain (ie, the primary outcome measure at the primary end point of 6 weeks) of just −14.4 mm (visual analog scale, 0–100) would have shown a larger effect size and exceeded the minimum clinically important difference for that measure.36–38

Thank you for the opportunity to comment on this most interesting paper. We appreciate the opportunity for a dialogue with the authors and believe that further discussion and debate can ultimately enhance both clinical practice and clinical research.

Footnotes

  • Dr James Dunning is the President of the American Academy of Manipulative Therapy (AAMT). Through Spinal Manipulation Institute (SMI) and Dry Needling Institute (DNI), AAMT provides postgraduate training programs in dry needling and spinal manipulation to licensed physical therapists, osteopaths, and medical doctors. Drs James Dunning, Raymond Butts, and Thomas Perreault are senior instructors for SMI and DNI.

  • This letter was posted as a Rapid Response on September 15, 2014 at ptjournal.apta.org.

  • © 2014 American Physical Therapy Association

References

  1. ↵
    1. Cotchett MP,
    2. Munteanu SE,
    3. Landorf KB
    . Effectiveness of trigger point dry needling for plantar heel pain: a randomized controlled trial. Phys Ther. 2014;94:1083–1094.
    OpenUrlAbstract/FREE Full Text
  2. ↵
    1. Tough EA,
    2. White AR,
    3. Richards S,
    4. Campbell J
    . Variability of criteria used to diagnose myofascial trigger point pain syndrome: evidence from a review of the literature. Clin J Pain. 2007;23:278–286.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    1. Lucas N,
    2. Macaskill P,
    3. Irwig L,
    4. et al
    . Reliability of physical examination for diagnosis of myofascial trigger points: a systematic review of the literature. Clin J Pain. 2009;25:80–89.
    OpenUrlCrossRefPubMedWeb of Science
  4. ↵
    1. Myburgh C,
    2. Larsen AH,
    3. Hartvigsen J
    . A systematic, critical review of manual palpation for identifying myofascial trigger points: evidence and clinical significance. Arch Phys Med Rehabil. 2008;89:1169–1176.
    OpenUrlCrossRefPubMed
  5. ↵
    1. Travell JG,
    2. Simons DG
    . Myofascial Pain and Dysfunction: The Trigger Point Manual. Vol 1. Baltimore, MD: Williams & Wilkins; 1983.
  6. ↵
    1. Travell JG,
    2. Simons DG
    . Myofascial Pain and Dysfunction: The Trigger Point Manual. Vol 2. Baltimore, MD: Williams & Wilkins; 1992.
  7. ↵
    1. Lew PC,
    2. Lewis J,
    3. Story I
    . Inter-therapist reliability in locating latent myofascial trigger points using palpation. Man Ther. 1997;2:87–90.
    OpenUrlCrossRefPubMed
  8. ↵
    1. Sciotti VM,
    2. Mittak VL,
    3. DiMarco L,
    4. et al
    . Clinical precision of myofascial trigger point location in the trapezius muscle. Pain. 2001;93:259–266.
    OpenUrlCrossRefPubMedWeb of Science
  9. ↵
    1. Myburgh C,
    2. Lauridsen HH,
    3. Larsen AH,
    4. Hartvigsen J
    . Standardized manual palpation of myofascial trigger points in relation to neck/shoulder pain; the influence of clinical experience on inter-examiner reproducibility. Man Ther. 2011;16:136–140.
    OpenUrlCrossRefPubMed
  10. ↵
    1. Al-Shenqiti AM,
    2. Oldham JA
    . Test-retest reliability of myofascial trigger point detection in patients with rotator cuff tendonitis. Clin Rehabil. 2005;19:482–487.
    OpenUrlAbstract/FREE Full Text
  11. ↵
    1. Gerwin RD,
    2. Shannon S,
    3. Hong CZ,
    4. et al
    . Interrater reliability in myofascial trigger point examination. Pain. 1997;69:65–73.
    OpenUrlCrossRefPubMedWeb of Science
  12. ↵
    1. Hsieh CY,
    2. Hong CZ,
    3. Adams AH,
    4. et al
    . Interexaminer reliability of the palpation of trigger points in the trunk and lower limb muscles. Arch Phys Med Rehabil. 2000;81:258–264.
    OpenUrlCrossRefPubMedWeb of Science
  13. ↵
    1. Levoska S,
    2. Keinänen-Kiukaanniemi S,
    3. Bloigu R
    . Repeatability of measurement of tenderness in the neck-shoulder region by a dolorimeter and manual palpation. Clin J Pain. 1993;9:229–235.
    OpenUrlCrossRefPubMedWeb of Science
  14. ↵
    1. Njoo KH,
    2. Van der Does E
    . The occurrence and inter-rater reliability of myofascial trigger points in the quadratus lumborum and gluteus medius: a prospective study in non-specific low back pain patients and controls in general practice. Pain. 1994;58:317–323.
    OpenUrlCrossRefPubMedWeb of Science
  15. ↵
    1. Cotchett MP,
    2. Landorf KB,
    3. Munteanu SE,
    4. Raspovic AM
    . Consensus for dry needling for plantar heel pain (plantar fasciitis): a modified Delphi study. Acupunct Med. 2011;29:193–202.
    OpenUrlAbstract/FREE Full Text
  16. ↵
    1. Imamura M,
    2. Fischer AA,
    3. Imamura ST,
    4. et al
    . Treatment of myofascial pain components in plantar fasciitis speeds up recovery: documentation by algometry. J Musculoskelet Pain. 1998;6:91–110.
    OpenUrlCrossRefWeb of Science
  17. ↵
    1. Perez-Millan R,
    2. Foster L
    . Low-frequency electroacupuncture in the management of refractory plantar fasciitis: a case-series. Med Acupunct. 2001;13:1–7.
    OpenUrl
  18. ↵
    1. Tillu A,
    2. Gupta S
    . Effect of acupuncture treatment on heel pain due to plantar fasciitis. Acupunct Med. 1998;16:66–68.
    OpenUrlAbstract/FREE Full Text
  19. ↵
    1. Cotchett MP,
    2. Landorf KB,
    3. Munteanu SE
    . Effectiveness of dry needling and injections of myofascial trigger points associated with plantar heel pain: a systematic review. J Foot Ankle Res. 2010;3:18.
    OpenUrlCrossRefPubMed
  20. ↵
    1. Kumnerddee W,
    2. Pattapong N
    . Efficacy of electro-acupuncture in chronic plantar fasciitis: a randomized controlled trial. Am J Chin Med. 2012;40:1167–1176.
    OpenUrlCrossRefPubMed
  21. ↵
    1. Dunning J,
    2. Butts R,
    3. Mourad F,
    4. et al
    . Dry needling: a literature review with implications for clinical practice guidelines. Phys Ther Rev. 2014;19:252–265.
    OpenUrlCrossRefPubMed
  22. ↵
    1. Chae Y,
    2. Chang DS,
    3. Lee SH,
    4. et al
    . Inserting needles into the body: a meta-analysis of brain activity associated with acupuncture needle stimulation. J Pain. 2013;14:215–222.
    OpenUrlCrossRefPubMedWeb of Science
  23. ↵
    1. Biella G,
    2. Sotgiu ML,
    3. Pellegata G,
    4. et al
    . Acupuncture produces central activations in pain regions. Neuroimage. 2001;14(1 pt 1):60–66.
    OpenUrlCrossRefPubMedWeb of Science
  24. ↵
    1. Hsieh JC,
    2. Tu CH,
    3. Chen FP,
    4. et al
    . Activation of the hypothalamus characterizes the acupuncture stimulation at the analgesic point in human: a positron emission tomography study. Neurosci Lett. 2001;307:105–108.
    OpenUrlCrossRefPubMedWeb of Science
  25. ↵
    1. Hui KK,
    2. Liu J,
    3. Makris N,
    4. et al
    . Acupuncture modulates the limbic system and subcortical gray structures of the human brain: evidence from fMRI studies in normal subjects. Hum Brain Mapp. 2000;9:13–25.
    OpenUrlCrossRefPubMedWeb of Science
  26. ↵
    1. Napadow V,
    2. Makris N,
    3. Liu J,
    4. et al
    . Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI. Hum Brain Mapp. 2005;24:193–205.
    OpenUrlCrossRefPubMedWeb of Science
  27. ↵
    1. Napadow V,
    2. Kettner N,
    3. Liu J,
    4. et al
    . Hypothalamus and amygdala response to acupuncture stimuli in carpal tunnel syndrome. Pain. 2007;130:254–266.
    OpenUrlCrossRefPubMedWeb of Science
  28. ↵
    1. Almeida RT,
    2. Perez AC,
    3. Francischi JN,
    4. et al
    . Opioidergic orofacial antinociception induced by electroacupuncture at acupoint St36. Braz J Med Biol Res. 2008;41:621–626.
    OpenUrlCrossRefPubMed
  29. ↵
    1. Almeida RT,
    2. Duarte ID
    . Nitric oxide/cGMP pathway mediates orofacial antinociception induced by electroacupuncture at the St36 acupoint. Brain Res. 2008;1188:54–60.
    OpenUrlCrossRefPubMedWeb of Science
  30. ↵
    1. Baldry P
    . Management of myofascial trigger point pain. Acupunct Med. 2002;20:2–10.
    OpenUrlAbstract/FREE Full Text
  31. ↵
    1. Cagnie B,
    2. Dewitte V,
    3. Barbe T,
    4. et al
    . Physiologic effects of dry needling. Curr Pain Headache Rep. 2013;17:348.
    OpenUrlCrossRefPubMed
  32. ↵
    1. Roxas M
    . Plantar fasciitis: diagnosis and therapeutic considerations. Altern Med Rev. 2005;10:83–93.
    OpenUrlPubMedWeb of Science
  33. ↵
    1. Singh D,
    2. Angel J,
    3. Bentley G,
    4. Trevino SG
    . Fortnightly review: plantar fasciitis. BMJ. 1997;315:172–175.
    OpenUrlFREE Full Text
  34. ↵
    1. Wearing SC,
    2. Smeathers JE,
    3. Urry SR,
    4. et al
    . The pathomechanics of plantar fasciitis. Sports Med. 2006;36:585–611.
    OpenUrlCrossRefPubMedWeb of Science
  35. ↵
    1. Ebrahim A,
    2. Ahmed G,
    3. Elsayed E,
    4. Sarhan R
    . Effect of electroacupuncture TENS, stretching exercises, and prefabricated insole in patients with plantar fasciits. The Scientific Journal of Al-Azhar Medical University. 2007;28:1–10.
    OpenUrl
  36. ↵
    1. Copay AG,
    2. Subach BR,
    3. Glassman SD,
    4. et al
    . Understanding the minimum clinically important difference: a review of concepts and methods. Spine J. 2007;7:541–546.
    OpenUrlCrossRefPubMedWeb of Science
    1. Beaton DE,
    2. Bombardier C,
    3. Katz JN,
    4. et al
    . Looking for important change/differences in studies of responsiveness. OMERACT MCID Working Group. Outcome Measures in Rheumatology. Minimal Clinically Important Difference. J Rheumatol. 2001;28:400–405.
    OpenUrlAbstract/FREE Full Text
  37. ↵
    1. Beaton DE
    . Understanding the relevance of measured change through studies of responsiveness. Spine (Phila Pa 1976). 2000;25:3192–3199.
    OpenUrlCrossRef
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On “Effectiveness of trigger point dry needling…” Cotchett MP, Munteanu SE, Landorf KB. Phys Ther. 2014;94:1083–1094.
James Dunning, Raymond Butts, Thomas Perreault
Physical Therapy Nov 2014, 94 (11) 1677-1680; DOI: 10.2522/ptj.2014.94.11.1677

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On “Effectiveness of trigger point dry needling…” Cotchett MP, Munteanu SE, Landorf KB. Phys Ther. 2014;94:1083–1094.
James Dunning, Raymond Butts, Thomas Perreault
Physical Therapy Nov 2014, 94 (11) 1677-1680; DOI: 10.2522/ptj.2014.94.11.1677
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