Figures
Task-Related Training in Huntington's Disease (TRAIN-HD) CONSORT flow diagram.
Tables
Mean (SD) [Range] Scores on Disease-Specific Measures for All Participants at Assessment 1 (Baseline), Categorized by Control Group and Intervention Groupa
↵a Total functional capacity: range=0–13, higher is better; Unified Huntington's Disease Rating Scale (UHDRS) Cognitive Score: range=0–no maximum value, higher score is better; UHDRS Functional Score: range=0–25, higher score is better; UHDRS Total Motor Score: range=0–124, lower score is better; disease burden score: lower score is better.
b n=12.
Examples of Goals Set for 3 Different Participants in the Intervention Group Using Goal Attainment Scaling (GAS)a
↵a The current level of skill attainment (determined within the first 3 intervention sessions) was set at a score of −1; the expected outcome at the end of the intervention was set at a score of 0; a somewhat better outcome than expected was set at 1; a much better outcome than expected was set at a score of 2; a worse outcome than expected was set at a score of −2. The scores at the end of the intervention were determined by the intervention therapist, either based on direct observation (all 3 examples here) or by participant interview (if self-report).
Unadjusted Descriptive Statistics Split by Treatment Group for Each Outcome at Assessments 1, 2, and 3a
↵a Assessment 1 was performed at baseline, assessment 2 at week 8, and assessment 3 at week 16. The ANCOVA controlled for sex, disease burden score, Unified Huntington's Disease Rating Scale (UHDRS) Total Motor Score, Berg Balance Scale score, and score of variable in question at assessment 1 (complete case analysis). ANCOVA=analysis of covariance, HDQoL=Huntington's Disease Health-Related Quality of Life.
b Effect sizes are calculated from the adjusted treatment effect, and the standard error and sample size are calculated from the ANCOVA.
c n=27.
Issue highlights
